Inter has turned to former Lazio head coach Stefano Pioli as the man to turn the club's stuttering start to the season around.
The Nerazzurri sacked Frank de Boer last week following their 1-0 Serie A defeat to Sampdoria, the Dutchman having only overseen two wins from their previous eight matches in all competitions.
Marcelino and Pioli were heavily linked to take over as De Boer's replacement, but it is the latter who has been tasked with reviving Inter's fortunes.
Pioli, 51, has agreed to a two-year contract at San Siro and will be presented to the media on Thursday before Inter plays the Milan derby after the international break.
Inter becomes Pioli's 11th club, with his previous tenure at Lazio having seen him guide the club to third place in his first season. His second campaign was not as prosperous and he was sacked in April after a 4-1 defeat to city rival Roma.
Despite significant investment ahead of the 2016-17 season, Inter has struggled to live up to expectations with only five wins in 12 league matches. It currently sits 13 points behind Serie A leader Juventus, and 12 ahead of bottom side Crotone, which it beat 3-0 on Sunday.
The victory over Crotone was under the guidance of interim boss Stefano Vecchi, but that only lifted Inter into ninth position.
Hopes of a strong European campaign are also hanging in the balance as Inter sits bottom of Europa League Group K after three defeats in four matches.