Aaron Cresswell was handed his first England call-up on Monday, while Jordan Pickford was also drafted in as Danny Drinkwater and Fraser Forster withdrew.
Gareth Southgate's side hosts Scotland in a World Cup qualifier on Friday and faces Spain four days later, with that Wembley friendly affording the interim coach the opportunity to assess his options.
And he will have 26-year-old West Ham fullback Cresswell at his disposal following Drinkwater's injury-enforced withdrawal, though the nature of his setback was not disclosed.
Southampton goalkeeper Forster's abdominal problem sees Pickford handed a late call-up, as happened with the last squad.
if you're in the @England squad!@Aaron_Cresswell has received his first senior England call-up! https://t.co/gZSeTA6LbO
#COYI pic.twitter.com/BSY27HwJGB
— West Ham United (@WestHamUtd) November 7, 2016
The 22-year-old produced a stunning display on Saturday to help Sunderland record its first Premier League win of the season at Bournemouth.
It is thought Cresswell's inclusion is also to cover for Danny Rose, who has been struggling with hamstring and foot problems.
England drew in Slovenia last time, but still tops Group F with seven points from three matches.