What happened to Michigan State on Friday afternoon was historic, and certainly no one saw it coming. But this isn't the first time a massive favorite has laid an egg in the first round of the NCAA Tournament.
The Spartans' loss to Middle Tennessee in the first-round was among the largest point spread upsets in March Madness, coming in behind only Missouri, South Carolina and Iowa State's losses as No. 2 seeds. Tom Izzo's group closed at -16.5 at most Nevada sports books and fell, 90-81, to the Blue Raiders.
MORE: Biggest first-round chokes in NCAA Tournament history
Information is courtesy of KillerSports.com's database. Odds are not universally available past 1990.
Norfolk State vs. Missouri, 2012 first round (-21)
Led by Kyle O'Quinn, Norfolk State knocked off No. 2-seeded Missouri, 86-84. That same week, 15-seeded Lehigh knocked off Duke as a 12-point dog.
Coppin State vs. South Carolina, 1997 first round (-18.5)
No. 15 seed Coppin State closed the game on a 38-18 run and blew out South Carolina, 78-65.
Hampton vs. Iowa State, 2001 first round (-17.5)
Hampton beat Iowa State 59-58 in an ugly game. It was the Pirates' sixth season in Division I.
UAB vs. Iowa State, 2014 first round (-14.5)
Iowa State is back on the list, 13 years later. No. 14 UAB held on late to win 60-59 despite trialing by double digits.
Florida Gulf-Coast vs. Georgetown, 2013 first round (-14)
Dunk City dropped 54 points to win 78-68 and take the nation by storm for that one week in 2013 as a 15 seed.
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