Javier Mascherano has been forced to miss Barcelona's LaLiga clash against Athletic Bilbao with illness, while Andres Iniesta is absent with a thigh injury.
Both players missed training on Friday, with Iniesta ruled out, before the club also confirmed on Twitter Mascherano would play no part at the San Mames.
Ernesto Valverde returns to his old club with Thomas Vermaelen, Arda Turan, Aleix Vidal and Ousmane Dembele also out.
Bilbao 13/8 Double Chance v Barca
Javier Mascherano has a fever and will not play against Athletic Club. His availability will depend on the evolution of his illness #FCBlive
— FC Barcelona (@FCBarcelona) October 28, 2017
Jordi Alba has returned from three games out with a thigh injury, however, and is fit for the trip ot the Basque Country.