The NFL got a surprising divisional upset on "Monday Night Football" in Week 10 when the Commanders beat the undefeated Eagles. Will the league get another one in another divisional matchup?
LIVE: Follow SN's updates from 49ers vs. Cardinals
The Monday night game this week will feature a couple of NFC West teams doing battle. The 49ers will travel to State Farm Stadium to face the Cardinals as each looks to improve their record and return to the playoffs in 2022.
Both the 49ers and Cardinals have had their share of struggles this season. San Francisco had issues with injuries while Arizona's offense hasn't been consistent from week to week.
Still, both are very much in the playoff race, and San Francisco would be the NFC's No. 7 seed if the postseason began today. They certainly still have a shot at the division title, too, while the Cardinals could make some noise if they get on a well-timed hot streak.
MORE: Watch Cardinals vs. 49ers live with fuboTV (free trial)
But who will have the advantage on "Monday Night Football" in Week 11? Here's everything to know about the Cardinals vs. 49ers matchup ahead of ESPN's broadcast.
Who plays on 'Monday Night Football' tonight?
- Matchup: 49ers at Cardinals
- Location: State Farm Stadium in Glendale, Ariz.
The Cardinals (4-6) are set to host the 49ers (5-4) in a Week 11 game that could prove crucial in determining whether one or both NFC West teams can make a pushes toward the playoffs.
Arizona is in need of a win to keep it from falling three games below .500. The team has endured an up-and-down season to date, but just defeated the Rams in Week 10 with backup quarterback Colt McCoy starting. Kyler Murray missed the contest due to a hamstring injury.
Without Murray again, the Cardinals will count on DeAndre Hopkins to carry the passing game through McCoy, while rookie Trey McBride looks to help replace the impact of the injured Zach Ertz.
As for the 49ers, they are coming off a 22-16 win over the Chargers on "Sunday Night Football" and can move into a tie for first place in the division with a win. Jimmy Garoppolo will be asked to manage an offense comprised of weapons like Christian McCaffrey, Deebo Samuel, Brandon Aiyuk and George Kittle against what has been a stout Arizona defense this season.
If the Cardinals can beat the 49ers, it would put the two teams in a neck-and-neck race for a potential wild-card spot along with the Commanders. If the 49ers win, their playoff odds will increase significantly while Arizona might have a tough time making it back to the postseason.
Needless to say that Kyle Shanahan and Kliff Kingsbury should both be amped up for this contest.
What time is the NFL game tonight?
- Date: Monday, Nov. 21
- Start time: 8:15 p.m. ET
The 49ers-Cardinals game will kickoff at 8:15 p.m. ET in Week 11. All "Monday Night Football" games are set to begin at that time in 2022 with the exception of the two games in the Week 2 doubleheader.
That said, the 49ers are located in the Western time zone, so the game for viewers there will begin at 5:15 p.m. local time. Meanwhile, the Cardinals are in Arizona, which is a part of the Mountain time zone, so it will be 6:15 p.m. local time when the game begins there.
Arizona vs. San Francisco will be broadcast by ESPN. Joe Buck (play-by-play) and Troy Aikman (analyst) will be on the call in the booth and Lisa Salters will serve as the sideline reporter. There is no Manningcast in Week 11.
What channel is 'Monday Night Football' on tonight?
- Game: 49ers at Cardinals
- Date: Monday, Nov. 21
- TV channel: ESPN (U.S.) | TSN 1/3/4, RDS 2 (Canada)
- Live stream: ESPN app | ESPN.com | ESPN+ | fuboTV | DAZN (Canada)
Per usual, ESPN will broadcast "Monday Night Football." That said, there are other ways for viewers to watch the game with and without cable.
Those with cable subscriptions will be able to watch the game free on ESPN.com or the ESPN app on devices where it is supported. Additionally, NFL fans with an ESPN+ subscription will be able to view the contest there as the game airs on ESPN.
There will not be any simulcast of "Monday Night Football" in Week 11. The "Manningcast" won't return until Week 13, the first week of December. As such, fans will have to wait a while to hear the Manning brothers call a game.
Cord-cutters can find the game on fuboTV, which offers a free trial.
In Canada, fans can watch the game on TSN 1/3/4, RDS 2, or with DAZN, which carries every NFL game.
NFL live stream for Cardinals vs. 49ers
The Cardinals vs. 49ers contest will be broadcast on ESPN in the United States, but there are other ways that fans will be able to watch the game.
"Monday Night Football" will also be streamed on the ESPN app and ESPN.com for those with a cable subscription. Those without cable can still watch the game on ESPN+ with a subscription to the streaming service.
Cord-cutters can also access Monday night's matchup via fuboTV, which offers a free trial. FuboTV carries the ESPN family of networks in addition to CBS, Fox, and NFL Network, providing football fans an opportunity to tune in to football action all season.