"Monday Night Football" comes with a twist this week: the game between the 49ers and Cardinals will be played in Mexico City. Fans of the "Manningcast" will be disappointed, though, as Peyton and Eli Manning are still on a break from their popular broadcast.
This is their second break of the season. The Manning brothers sat out Weeks 5 and 6 in October and are taking time off in November, a stretch that began with the Commanders' upset of the then-undefeated Eagles.
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Peyton and Eli will take another break at the end of the regular season before returning for ESPN's wild-card playoff broadcast in January.
Here's what you need to know about when "Monday Night Football with Peyton and Eli" will be back on the air, along with a full "Manningcast" schedule.
MORE: Watch 'Monday Night Football' live with fuboTV (free trial)
When is the next 'Manningcast'?
Peyton and Eli Manning are set to return from their latest break in Week 13, when the Buccaneers host the Saints on Dec. 5.
Saints vs. Buccaneers will be the first of three consecutive "Monday Night Football" broadcasts for the Manning brothers. Peyton and Eli will also host a "Manningcast" for Patriots vs. Cardinals on Dec. 12 and Rams vs. Packers on Dec. 19.
After taking one final break, the "Manningcast" will return for ESPN's Wild Card Weekend game on Jan. 16.
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How to watch the Manning brothers on 'Monday Night Football'
- TV channel: ESPN2
- Live stream: ESPN.com, ESPN App, ESPN+, fuboTV
Each broadcast of "Monday Night Football with Peyton and Eli" airs on ESPN2. In Week 15 and Wild Card Weekend, the "Manningcast" broadcast will be simulcast on ESPN's streaming service, ESPN+.
Cord-cutters can stream the "Manningcast" with fuboTV, which carries the ESPN family of networks and offers a free trial.
'Manningcast' schedule 2022
"Monday Night Football with Peyton and Eli" has aired six times this season and will air another four times:
| Week | Date | Matchup |
| 1 | Sept. 12 | Broncos vs. Seahawks |
| 3 | Sept. 26 | Cowboys vs. Giants |
| 4 | Oct. 3 | Rams vs. 49ers |
| 7 | Oct. 24 | Bears vs. Patriots |
| 8 | Oct. 31 | Bengals vs. Browns |
| 9 | Nov. 7 | Ravens vs. Saints |
| 13 | Dec. 5 | Saints vs. Buccaneers |
| 14 | Dec. 12 | Patriots vs. Cardinals |
| 15 | Dec. 19 | Rams vs. Packers |
| Wild Card | Jan. 16 | TBD |
