Petra Kvitova has withdrawn from the French Open ahead of her opening match Monday because of a forearm injury.
The two-time Grand Slam champion had been due to face Sorana Cirstea in the first round, but Kvitova announced her "really tough decision" just hours before she was due on Court Suzanne Lenglen.
The world No. 6 retired from her last-16 match at the Internazionali d'Italia earlier this month and revealed Monday she had been playing through pain in recent weeks.
A scan on Sunday confirmed the Czech star would need to skip Roland Garros.
Kvitova post on Twitter: "I'm so disappointed to have to announce my withdrawal from Roland Garros.
"I've had pain in my left forearm for a few weeks and, last night, an MRI confirmed a grade two tear, which unfortunately could get a lot worse if I play today.
Sorry to have to inform you of some bad news this morning pic.twitter.com/snxhJkPRuh
— Petra Kvitova (@Petra_Kvitova) May 27, 2019
"Two years ago, I made my comeback here at Roland Garros, so I'm truly sad not to be able to play here this year.
"It is a really tough decision to make, but I wish the tournament all the best for a successful event and can't wait to be back in 2020."
Her best performance at the French Open saw her reach the semifinals in 2012, where she lost to eventual champion Maria Sharapova.
Kvitova, 29, was the victim of a career-threatening knife attack in late 2016 but returned to the court and earlier this year reached the final at the Australian Open, her first in a major since the incident.