England will be without Maro Itoje for their final Six Nations match against Scotland.
Lock Itoje has returned to Saracens to continue his recovery from a knee injury after being left out of Eddie Jones' 31-man training squad ahead of Saturday's match at Twickenham.
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The 24-year-old sustained the problem in England's tournament opener against Ireland on February 2 and was thought to be in the running for a return against Italy until he limped out of a training session last week.
Charlie Ewels was called up to replace Itoje and the Bath second row retains his spot in a squad that includes uncapped quartet Ben Earl, Elliott Stooke, Marcus Smith and Ollie Thorley.
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England can win the Six Nations title if they beat Scotland and Wales fail to beat Ireland in Cardiff.
Eddie Jones calls up 31 players to prepare for #ENGvSCO clash at Twickenham
— England Rugby (@EnglandRugby) March 11, 2019
See who's in https://t.co/ppxrhT05yk pic.twitter.com/tBrhOljdO4