Despite a rough ending for Texans -2.5 bettors, Week 9 was a big week for chalk bettors. Favorites ended Week 9 posting an impressive cover rate, covering in 10 of 14 games. Will that remain the case in the next slate of games?
Week 10 is again a 14-game slate, kicking off on Thursday night with the Bears (-3.5) hosting the Panthers, two franchises that shook up the 2023 NFL Draft after Chicago dealt the No. 1 pick for DJ Moore and draft capital. Sunday's slate starts off with the final game of the 2023 International Series between the Patriots (+1.5) and Colts in Frankfurt, Germany.
The rest of the Sunday slate should be entertaining from a viewers' standpoint, with 10 of the 11 games featuring one-possession spreads. The lone multi-possession spread of Sunday's slate sees the Cowboys laying 16 points at home against the (likely) Tommy DeVito-led Giants. The Sunday night and Monday night games between the Jets-Raiders and Bills-Broncos might not be the most appealing, but all it takes is a wager on one of those prime-time games to add a layer of intrigue.
Below, we'll look at the latest odds for Week 10 from Caesars Sportsbook and offer up a couple of early bets to consider. Keep in mind these lines will move throughout the week as we get updates on the playing status of key starters and betting limits increase.
NFL odds Week 10
Odds courtesy of Caesars Sportsbook
| Game | Spread |
| Chicago Bears vs. Carolina Panthers | CHI -4 (-110) |
| New England Patriots vs. Indianapolis Colts | NE +1.5 (-110) |
| Baltimore Ravens vs. Cleveland Browns | BAL -6 (-110) |
| Cincinnati Bengals vs. Houston Texans | CIN -7 (+100) |
| Minnesota Vikings vs. New Orleans Saints | MIN +2.5 (-110) |
| Tampa Bay Buccaneers vs. Tennessee Titans | TB -1 (-110) |
| Jacksonville Jaguars vs. San Francisco 49ers | JAX +3 (-110) |
| Pittsburgh Steelers vs. Green Bay Packers | PIT -3 (-120) |
| Arizona Cardinals vs. Atlanta Falcons | ARI +1.5 (-110) |
| Los Angeles Chargers vs. Detroit Lions | LAC +2.5 (-110) |
| Seattle Seahawks vs. Washington Commanders | SEA -6 (-115) |
| Dallas Cowboys vs. New York Giants | DAL -16 (-110) |
| Las Vegas Raiders vs. New York Jets | LV +1.5 (-110) |
| Buffalo Bills vs. Denver Broncos | BUF -7.5 (-110) |
NFL moneylines Week 10
| Game | Moneyline |
| Chicago Bears vs. Carolina Panthers | CHI -195 | CAR +162 |
| New England Patriots vs. Indianapolis Colts | IND -120 | NE +100 |
| Baltimore Ravens vs. Cleveland Browns | BAL -267 | CLE +215 |
| Cincinnati Bengals vs. Houston Texans | CIN -305 | HOU +240 |
| Minnesota Vikings vs. New Orleans Saints | NO -145 | MIN +122 |
| Tampa Bay Buccaneers vs. Tennessee Titans | TB -115 | TEN -105 |
| Jacksonville Jaguars vs. San Francisco 49ers | SF -165 | JAX +140 |
| Pittsburgh Steelers vs. Green Bay Packers | PIT -178 | GB +150 |
| Arizona Cardinals vs. Atlanta Falcons | ATL -125 | ARI +105 |
| Los Angeles Chargers vs. Detroit Lions | DET -145 | LAC +122 |
| Seattle Seahawks vs. Washington Commanders | SEA -267 | WAS +215 |
| Dallas Cowboys vs. New York Giants | DAL -1400 | NYG +800 |
| Las Vegas Raiders vs. New York Jets | NYJ -120 | LV +100 |
| Buffalo Bills vs. Denver Broncos | BUF -365 | DEN +285 |
NFL over/unders Week 10
| Game | Over/Under |
| Chicago Bears vs. Carolina Panthers | 39 |
| New England Patriots vs. Indianapolis Colts | 43.5 |
| Baltimore Ravens vs. Cleveland Browns | 37.5 |
| Cincinnati Bengals vs. Houston Texans | 48 |
| Minnesota Vikings vs. New Orleans Saints | 41 |
| Tampa Bay Buccaneers vs. Tennessee Titans | 38.5 |
| Jacksonville Jaguars vs. San Francisco 49ers | 46 |
| Pittsburgh Steelers vs. Green Bay Packers | 39 |
| Arizona Cardinals vs. Atlanta Falcons | 42.5 |
| Los Angeles Chargers vs. Detroit Lions | 48.5 |
| Seattle Seahawks vs. Washington Commanders | 45.5 |
| Dallas Cowboys vs. New York Giants | 38.5 |
| Las Vegas Raiders vs. New York Jets | 36 |
| Buffalo Bills vs. Denver Broncos | 47 |
NFL best bets for Week 10
*Odds and analysis as of Monday 11/6*
Patriots moneyline (+115) vs. Colts
Despite the Patriots owning an inferior record, it's still hard for us to justify the Gardner Minshew-led Colts being priced with a 57.45-percent implied win probability on a neutral field. In a game where we could easily make a case for the Patriots to be the favorites, we'll take a shot on New England at +115 to win outright.
Bengals-Texans OVER 46 (-110)
With how Joe Burrow and C.J. Stroud are playing right now, we can't make a case to bet the UNDER 46 (-110) on Sunday. Yes, the Bengals stop unit is stronger than Tampa Bay's, which likely results in Stroud coming back down to Earth, but both teams are capable of scoring 24-plus.
