Alex de Minaur has crashed out of the Paris Masters with a 6-3 6-4 loss to fellow young gun Stefanos Tsitsipas.
The Australian had lost his previous two matches agaisnt the Greek rising star and was unable to keep pace with his 21-year-old opponent on Friday morning (AEDT).
De Minaur dropped his opening service game of the contest and was unable to work his way back into the match as Tsitsipas broke again in the ninth game to take the first set.
Tsitsipas' third sevice break in the second set was enough to secure victory and set up a quarter-final showdown against 16-time grand slam champion Novak Djokovic.
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De Minaur, ranked 18th in the world, will instead turn his attention to the Next Gen ATP Finals in Milan next week.
Djokovic set up a tantalising clash with Tsitsipas after seeing off Kyle Edmund.
The world number one, who will lose top spot to Rafael Nadal next week, appeared to be under the weather but ground out a 7-6 (9-7) 6-1 victory.
He growled through a post-match interview, his voice indicating all was not entirely well, but Djokovic still had enough in the tank to see off his British opponent.
Edmund ended a losing streak of eight matches when winning through the first two rounds in Paris, and the former top-20 player pushed Djokovic hard in the opening set.
Neither man registered a break, but the contest became one-sided once Djokovic nudged ahead. He clinched his 50th match win of the season in a hurry, claiming 12 of the final 14 points.
Tsitsipas has won two of his three previous matches against the Serbian.
The most recent of those meetings came in Shanghai just three weeks ago, when Tsitsipas prevailed in a deciding set.