New Zealand will aim to successfully defend their title by seeing off the Wallabies in the Twickenham showpiece on Saturday, which marks the first the first time the pair have met in the final of the competition.
Australia beat the All Blacks to win the Rugby Championship in August and Lomu, who shares the World Cup record for tries with Bryan Habana on 15, believes Pocock and Hooper provide the key to the Wallabies' hopes of capturing the Webb Ellis Cup.
"If there's any team who can give New Zealand a run for their money then it's Australia because they're the only team to have beaten them this year," Lomu was quoted as saying by various outlets.
"The difference at the moment is that New Zealand only have Richie McCaw in their back row, while Australia have Hooper and Pocock working together. That gives them a different dimension at the breakdown.
"Their speed into the breakdown will give the All Blacks a real headache. It will be interesting to see how they deal with that.
"The backs will get praise for scoring tries, but matches are won up front and the breakdown will be what makes the difference.
"Australia playing two opensides [flankers] in Pocock and Hooper is a real threat to the All Blacks."