Great Britain takes on the United States in the Davis Cup World Group first round, while Switzerland's title defense could come to an early end.
Milos Raonic and Kei Nishikori will take center stage as Canada takes on Japan. Those players have staged tremendous matches in recent meetings as they have risen in world rankings.
Andy Murray will be in action in Glasgow as Great Britain meets the U.S., which will be led by John Isner. Murray led his side to a 3-1.
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Beating the Americans a second consecutive year will be a challenge, Murray said.
"I know Isner wasn't able to play," Murray said via Davis Cup website.
"Also it was on clay and I did say at the time I thought it was a strange surface choice, which I thought favored us, really.
"Obviously an indoor hard court is a quite neutral surface for everyone. It will be tough if they are all fit and well. It will be a tough one for us to win but it's possible."
At 111, James Ward is Great Britain's second singles player. And although its fortunes have waned, the U.S. have Isner and the in-form Donald Young.
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While Murray has an edge against either Isner or Young, the U.S. has a far superior doubles team in Bob and Mike Bryan. Murray and brother Jamie will represent the Britain.
Former U.S. tennis star Andre Agassi sees it as an even match, with an edge to the Americans.
"We have a big advantage in our doubles," he said, speaking to Britain's Sky Sports, "but you guys have a huge advantage with Murray.
"People think he's coming off a bad loss but I've got news for you; he's going to be ready to go in a week and he's going to be playing his best tennis in front of a home crowd."
That loss, to up-and-coming teen Borna Coric in Dubai last week, isn't indicative of Murray's play this year.
Nishikori is No. 4 in world rankings, with Raonic at No. 6. While Nishikori relies on court smarts and speed, Raonic brings a big serve and power game.
“It’s never easy to play against him — but I also enjoy playing with him,” said Nishikori, per The Globe and Mail of Toronto. “It’s always fun.”
Despite their on-court rivalry, Nishikori and Raonic are friendly off the court.
“We’re aware of what one another is doing,” Raonic said, “and when we are able to see each other, we point out those successes to one another and congratulate each other.”
Switzerland begins it title defense against Belgium, but neither Roger Federer nor Stan Wawrinka will play, That leaves Yann Marti (292) as their highest-ranked singles player.
With David Goffin part of the team, Belgium likely will be hard to stop on the indoor hard courts.
Elsewhere in the first round, Gilles Simon and Gael Monfils will lead France into its tie against Germany in Frankfurt. The winner of that tie will face either Great Britain or the USA.
There are also fierce rivalries taking place in both Europe and South America.
Novak Djokovic will lead Serbia into action against a Croatia in Kraljevo, but the Croats will be without Marin Cilic.
In Buenos Aires, where clay is the surface of choice, Argentina takes on Brazil.
Elsewhere, Australia travels to Ostrava to take on the Czech Republic, which will be without Tomas Berdych.
Fabio Fognini and Andreas Seppi lead Italy into a meeting with Kazakhstan.
Contributing: Sportal.com.au