Ireland captain Paul O'Connell and Wales skipper Sam Warburton will both reach landmark appearances in Saturday's crucial Six Nations clash in Cardiff.
O'Connell will lead out the men in green at the Millennium Stadium and collect his 100th Ireland cap in the process.
The second-rower's primary focus will be on leading his side to a fourth victory in this season's tournament and to the brink of a Grand Slam.
Head coach Joe Schmidt insists that talk of O'Connell's 100th appearance and whether the skipper will continue to play beyond this year's World Cup has been put to one side ahead of the match.
"I haven't spoken to him about anything other than what we might do at kick-off," he said.
"Paul is pretty happy with that, there's part of him that would love to play forever. He's incredibly motivated to play as long as he can.
"Whether 100 caps or not, he's been a fantastic leader and [part of] a group who lead with him and lead themselves."
Ireland head into the match brimming with confidence having racked up a record-equalling 10th straight victory by beating England 19-9 last time out.
Jamie Heaslip is Ireland's only change from that encounter, the number eight having returned to training after fracturing three vertebrae when he was kneed in the back by France's Paspal Pape in their second match of the tournament.
Looking to derail Ireland's momentum are a Wales side that still harbour hopes of winning the Six Nations themselves.
Warren Gatland's men also have a skipper who has a reason to celebrate, as Warburton will wear the armband for a record 34th time - surpassing Ryan Jones' previous benchmark.
Wales, who have named the same XV that beat France 20-13, bounced back from an opening-round loss to England with successive wins.
Another victory will put them back in the hunt for the Six Nations title and centre Jamie Roberts is keen to avenge several painful memories against Ireland - including a 2009 defeat in Cardiff that saw Ireland walk away as Grand Slam winners.
"I will never forget 2009, watching Ireland win the Grand Slam in our stadium," Roberts told the official Six Nations website.
"That is one of those moments in your career that drives you and motivates you I suppose. It's something you never want to happen again.
"Looking back on a personal note there have been more lows than highs against them. That is something I am quite keen to rectify."