Kylian Mbappe will not feature against Portugal on Saturday after he was left out of France's 23-man squad list for the Nations League fixture.
The Paris Saint-Germain forward suffered a hamstring problem against Nantes on October 31 and has not recovered in time to feature for his country in Lisbon.
Mbappe had already missed the friendly defeat to Finland earlier in the week, while it remains unclear if he will be ready for the upcoming Nations League clash with Sweden on Tuesday.
France boss Didier Deschamps had named the 21-year-old in his initial squad despite doubts over his fitness, though insisted at the time there was no conflict between club and country.
PSG had announced on Friday that Neymar will return from the Brazil squad to continue his recovery from a groin injury. Moise Kean is also back at the Ligue 1 club after being released from duty with Italy.
Thomas Tuchel's side are next in action on November 20, taking on Monaco, then host RB Leipzig four days later in the Champions League.