Darren Lehmann will miss Australia's three-match Twenty20 series against India after being diagnosed with deep vein thrombosis.
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Australia team doctor John Orchard confirmed head coach Lehmann is to spend a "day or two days" in hospital to recover.
Lehmann, who is already scheduled to skip next year's tour of the West Indies, will subsequently miss the T20 contests against India, which start in Adelaide on Tuesday, with batting coach Michael Di Venuto acting as interim coach.
"It's a condition that's got a very good outcome if you get it early, which we have," Orchard told Cricket Australia's official website.
"So it's all good news, but one of the factors associated with it is it's unwise to fly until you have stabilised the condition.
"So he will be absent from the Australian team camp for a short period. And that will depend on how long that will take for him to get stabilised and treated so they're happy to release him.
"He's very sensible about it and wants to put his health first so he's happy to hand over the reins to make sure he's going to be okay from a health perspective, which is what we expect."
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Australia won the five-match one-day international series against India 4-1, but were beaten by six wickets in the fifth contest on Saturday.
All-rounder Glenn Maxwell is hoping to be fit for the first T20 match having missed the final ODI with a bruised right knee.
"It's a bit of a race against time obviously with the series being so close together," Maxwell said.
"I'll just be doing everything I can, icing up over the next few days and I'll probably have a fitness test on either Monday or Tuesday."