Entering the second week of the AFL finals, coaches are required to make some big calls, with plenty riding on both semi finals as Geelong and Sydney await their oppositions.
Brisbane are set to regain Noah Answerth and Cam Rayner from suspension, while Oscar McInerney will need to be replaced following a nasty concussion against Richmond last week.
Veteran Mitch Robinson and youngster Jaxon Prior are likely to be the unfortunate ones to make way for Answerth and Rayner, while Darcy Fort is expected to be recalled.
Robinson collected 10 possessions from 61 per cent game time and struggled to meet the standards for a crucial final while Prior gathered 12 touches from even more time.
The former Blue hasn't been in the best form over the past couple weeks and is likely to make room.
Prior has been serviceable in the past few games but hasn't been able to hold his spot throughout the season, which is reason to suspect he won't for the semi final.
Melbourne are sweating on the availability of stars Christian Petracca and Charlie Spargo, who are touch-and-go to play on Friday night against the Lions.
Luke Dunstan, Tom McDonald and Toby Bedford are all on standby as the Demons hold their breath.
With that said, it is unlikely that Simon Goodwin will drop someone from the side as the club prepares to avoid a straight sets exit.
Collingwood will be forced into at least one change, with vice-captain Taylor Adams rupturing his groin in the narrow loss to Geelong.
However, Nathan Kreuger was the medical sub and came on late in the game, while coach Craig McRae is excited by his energy and ability to play at both ends.
This could mean that Mason Cox might make way for Kreuger, given he played less than half a game, (46 per cent), which resulted in six touches and two marks.
However, the Pies may choose to persist with Cox given his ability to stand up in big games, with the black-and-white army needing a miracle as they take on Fremantle.
The Dockers are unlikely to make any changes to their senior side that defeated Western Bulldogs.
Although, Matt Taberner got through a WAFL match over the weekend and could be brought in for Jye Amiss, despite the youngster stepping up in crucial moments against the Dogs.