Following an extraordinary Anzac Round, capped off by a come-from-behind win by Collingwood on Tuesday, all eyes turn to round seven.
St Kilda vs Port Adelaide
A crucial Friday night clash is upon us, with the top-of-the-table Saints taking on an in-form Port Adelaide side who have won three on the trot.
St Kilda are unlikely to break up a winning combination that took down Carlton on Sunday, unless they opt for more experience as Jack Billings returned through the VFL.
MORE: Injury List: Gold Coast skipper sidelined
For the Power, they too are coming off some impressive wins but will be forced into at least three changes, with Todd Marshall (concussion), Kane Farrell (Jaw) and captain Tom Jonas (suspension) all missing.
Charlie Dixon is likely to come back in while Lachie Jones and Jase Burgoyne are in waiting.
However, Jed McEntee might have bought himself another week in the seniors despite a very quiet showing in the win against West Coast.
Brisbane vs Fremantle
Brisbane's strong performance over GWS makes it three wins on the trot and it's hard to see another change to their line up.
Darcy Wilmot is one who could face the axe this week against Fremantle, given coach Chris Fagan may opt for a second ruck, bringing in Darcy Fort to combat Luke Jackson and Sean Darcy.
The Dockers could welcome back injured duo Sam Switkowski and Heath Chapman into the line-up while youngster Neil Erasmus is forcing his way into the side after a strong WAFL performance.
Brandon Walker has struggled at AFL level over the past couple weeks and could be a straight swap with Chapman while Michael Frederick's injury is the other likely change.
Sydney vs GWS
Sydney are forced into at least two changes, given the injuries to Robbie Fox (concussion) and Matt Roberts (knee).
John Longmire could welcome back Tom Hickey despite playing only three quarters in the VFL, while Lance Franklin, Dane Rampe and Tom McCartin are on track to feature.
If this is the case, Will Gould and Aaron Francis could make room while the under-performing Logan McDonald might face the axe.
As for their opponents, the Giants, they'll miss Sam Taylor and Adam Kennedy to long-term injuries in a vital blow to the side.
Tom Green will return from suspension as Callan Ward is sidelined with suspension, while recruit Toby Bedford will be around the mark.
Harry Rowston failed to impact the game last week and might be dropped for the crucial derby clash.
Western Bulldogs vs Hawthorn
After a stirring victory in the west, the Western Bulldogs only have one qualm, that being a Tom Liberatore injury (concussion).
Arthur Jones and Anthony Scott both failed to influence the game but are unlikely to be sent to the reserves following a comprehensive win.
For Hawthorn, ruckman Max Lynch suffered another concussion and is ruled out of this weekend's clash, meaning Lloyd Meek is likely to be recalled.
Mitch Lewis and Josh Ward may also return to the senior side which could see Seamus Mitchell and Jack Scrimshaw sent to the twos.
Melbourne vs North Melbourne
Melbourne welcomed back a host of their stars last week for the Anzac Day eve clash with Richmond and have a relatively healthy list.
Ben Brown and Tom McDonald played well in the VFL along with James Harmes and Luke Dunstan.
Tom Sparrow has been serviceable but could make room in the midfield for a more experienced player while Harrison Petty is on his last legs as a forward.
North Melbourne are hopeful that co-captain Jy Simpkin will be ready to go, pending a fitness test.
Hugh Greenwood and George Wardlaw also had handy games in the reserves, putting Will Phillips, Daniel Howe and Kayne Turner on notice.
West Coast vs Carlton
Uncertainty has rummaged through the West Coast Eagles as timelines and availabilities on players are few and far between.
Shannon Hurn is likely to return from injury while Xavier O'Neill is tipped to replace the injured Luke Shuey.
Zane Trew was quiet in the loss to the Power and could be the unlucky one.
Adam Saad will come back into the senior side if he passes a fitness test while Jesse Motlop is out due to suspension.
Paddy Dow, Jaxon Binns and Jack Carroll impressed in the VFL leaving Josh Honey and Ed Curnow vulnerable.
Given their stagnant style of play at the current time, Michael Voss may opt to add more speed into the lineup.
Essendon vs Geelong
Essendon will welcome back captain Zach Merrett from suspension but lost Jayden Laverde to injury.
Facing Jeremy Cameron and Tom Hawkins, Brad Scott could bring in Zach Reid to combat the dynamic duo.
After smashing the Swans in a Grand Final rematch, Geelong are unlikely to make any changes to their line-up.
However, if Jed Bews is passes concussion protocols then Brandon Parfitt may be pushed out.
Richmond vs Gold Coast
Nathan Broad will return from suspension while Jack Graham inches closer after a hamstring injury.
Maurice Rioli Jr. hurt himself on Monday night but the extent of injury is unknown.
Tylar Young is likely to make room for Broad while Rhyan Mansell could also face the axe.
For this important clash, Gold Coast lose co-captain Touk Miller after he tore his mensicus.
Alex Davies could come into the side as could Connor Blakely, while the form of Alex Sexton (5.5) in the VFL could push out Malcolm Rosas.
Adelaide vs Collingwood
Adelaide's injury list is the healthiest in the competition, with a host of players pushing for selection in the SANFL.
Ned McHenry, Patrick Parnell and Harry Schoenberg remain on the fringe but are unlikely to be given a crack this weekend, resulting in no changes for the Crows.
Collingwood somehow managed to escape Anzac Day with the all-important four points and need to back it up after a five-day break.
Nathan Murphy (concussion) and Taylor Adams (suspension) are expected to come back into the side at the expense of Trey Ruscoe and Will Kelly.
Nathan Krueger might be persisted with as a back-up ruckman while Reef McInnes was superb in the VFL.
If Scott Pendlebury (eye) doesn't get up, Josh Carmichael or Finlay Macrae could step into his role.
